Drew-Orleans Lou-Brees-iana

New York Giants quarterback, and New Orleans native, Eli Manning didn't quite get the homecoming he expected Monday night at the Superdome. Perhaps the reason had something to do with the 363 passing yards and five total touchdowns Drew Brees mixed in his roux of offensive ingredients in the Saints' 49-24 thrashing of the Giants' injury-laden defense. Who dat? Apparently not the 'G' men.

Byes: None

QB
Dan Orlovsky (Ind @ NE)  The UConn alum will get his first crack at the worst pass defense in the league for the twelfth straight week.
Matt Moore (Mia vs Oak)  Matt Moore has improved nicely since taking over in week six, averaging 17 points in November.
Alex Smith (SF vs StL)  Under rookie head coach Jim Harbaugh, Smith has been a solid play complementing a strong running game and even stronger defense.
RB
BenJarvus Green-Ellis (NE vs Ind)  The Ole Miss grad should have a 'firm' grip on a horrible Colts defensive unit, favored by 20+ points.
Jonathan Stewart (Car @ TB)  The Bucs' defense has been less than desirable this season. Stewart should get a few big runs up the middle with outside containment set up to attempt to stop DeAngelo Williams and Cam Newton.
C.J. Spiller (Buf vs Ten)  Spiller should get rushing and receiving yards, totaling around 100. Even if he doesn't score, the Clemson Tiger is a solid sleeper for week 13.
WR
Pierre Garcon (Ind @ NE)  The Colts' leading receiver will be the second option against the Patriots - a no-brainer.
Jason Avant (Phi @ Sea) Maclin will be inactive again. Avant had 25 points last week against New England.
Doug Baldwin (Sea vs Phi)  With Sidney Rice out for the season, Baldwin should get double figures at home versus Philly.
TE
Dustin Keller (NY Jets @ Was)  Keller found pay dirt twice last week. Washington's defense falls somewhere in the middle, giving up the 17th most points to tight ends.
Jacob Tamme (Ind @ NE)  Although Tamme only grabbed two catches last week versus Carolina, the match-up (Pats' defense) is just too ripe to pass up.
Heath Miller (Pit vs Cin)  Facing a top five defense, Big Ben's security net is Miller. He only had six points the first time these two teams met. Look for red zones targets to go in Heath's direction.
DEF

Tampa Bay vs Car
Minnesota vs Den
Washington vs NYJ

QB
Matt Ryan (Atl @ Hou)
Sam Bradford (StL @ SF)
RB
Steven Jackson (StL @ SF)
Rashard Mendenhall (Pit vs Cin)
WR
DeSean Jackson (Phi @ Sea)
Dwayne Bowe (KC @ Chi)
TE
Scott Chandler (Buf vs Ten)
Greg Olsen (Car @ TB)
DEF
Detroit @ NO
Miami vs Oak